
Monensin sodium salt
CAS No. 22373-78-0
Monensin sodium salt ( Monensin A | NSC 343257 | Rumensin )
产品货号. M13589 CAS No. 22373-78-0
Monensin sodium salt 是由肉桂链霉菌 (Streptomyces cinnamonensis) 分泌的抗生素。Monensin sodium salt 是一种介导 Na+/H+ 交换的离子载体。Monensin sodium salt 引起细胞多泡体 (MVBs) 增大并调节外泌体的分泌。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
50MG | ¥243 | 有现货 |
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100MG | ¥340 | 有现货 |
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200MG | ¥470 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Monensin sodium salt
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Monensin sodium salt 是由肉桂链霉菌 (Streptomyces cinnamonensis) 分泌的抗生素。Monensin sodium salt 是一种介导 Na+/H+ 交换的离子载体。Monensin sodium salt 引起细胞多泡体 (MVBs) 增大并调节外泌体的分泌。
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产品描述Sodium Monensin, isolated from Streptomyces cinnamonensis, is a well-known representative of naturally polyether ionophore antibiotics.
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体外实验Cell Viability Assay Cell Line:SCC9, SCC25, and GM-38 cell lines Concentration:1-5 μM Incubation Time:48 h Result:Resulted in a marked decrease in viability in a dose-dependent manner.Apoptosis Analysis Cell Line:SCC25 cells Concentration:1 μM, or 5 μM Incubation Time:24 hours Result:Induced a potent apoptotic response.Western Blot Analysis Cell Line:SCC9 and SCC25 cells Concentration:0.1 μM, or 1 μM Incubation Time:24 hours Result:Induced approximately a 50% inhibition of EGF-treated SCC9 cells with respect to pEGFR and its downstream targets pAKT and pERK.
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体内实验Animal Model:Multiple intestinal neoplasia (Min) mice (four-week-old) Dosage:10 mg/kg Administration:Orally application; daily; for 6 weeks Result:Suppressed progression of the intestinal tumors without any sign of toxicity on normal mucosa.
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同义词Monensin A | NSC 343257 | Rumensin
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通路Others
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靶点Other Targets
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受体Others
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研究领域Other Indications
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适应症——
化学信息
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CAS Number22373-78-0
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分子量692.85
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分子式C36H61NaO11
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纯度>98% (HPLC)
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溶解度Ethanol: 100 mg/mL (144.33 mM)
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SMILESCC[C@]1(CC[C@@H](O1)[C@@]2(CC[C@@]3(O2)C[C@@H]([C@H]([C@H](O3)[C@@H](C)[C@H]([C@H](C)C(=O)[O-])OC)C)O)C)[C@H]4[C@H](C[C@@H](O4)[C@@H]5[C@H](C[C@H]([C@@](O5)(CO)O)C)C)C.[Na+]
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Pinkerton M, et al. J Mol Biol, 1970, 49(3), 533-546.
产品手册




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